Common Blood Disorders

Leukemia is a type of cancer that affects the blood and bone marrow. Leukemia begins in a cell in the bone marrow. The cell undergoes a change and becomes a type of leukemia cell. Once the marrow cell undergoes a leukemic change, the leukemia cells may grow and survive better than normal cells. Over time, the leukemia cells crowd out or suppress the development of normal cells. The rate at which leukemia progresses and how the cells replace the normal blood and marrow cells are different with each type of leukemia.
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Myeloma, also known as multiple myeloma, is a cancer arising from plasma cells, a type of white blood cell which is made in the bone marrow. Bone marrow is the ‘spongy’ material found in the centre of the larger bones in the body. In myeloma, plasma cells become abnormal, multiply uncontrollably and release only one type of antibody known as paraprotein, which has no useful function. It is often through the measurement of this paraprotein that myeloma is diagnosed and monitored.
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Lymphoma is a cancer of the lymphatic system. There are two main types – Hodgkin lymphoma and non-Hodgkin lymphoma.
Hodgkin lymphoma is a cancer of the lymphatic system – part of the body’s immune system. Only about 1 in 5 of all lymphomas diagnosed (20%) are Hodgkin lymphoma.
Non-Hodgkin lymphoma (NHL) is a cancer of the lymphatic system. NHL is the fifth most common cancer in the UK. Around 11,500 people are diagnosed with it each year. There are many types of NHL. Some grow very slowly and may not need treatment for months or years. In some cases they may never need treatment. Other types grow quickly and need treatment soon after diagnosis.
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Thrombosis and Haemostasis
Every year, thousands of people in the UK develop a blood clot in a vein. It’s known as venous thromboembolism (VTE) and is a serious, potentially fatal, medical condition. VTE is the collective name for: Deep vein thrombosis (DVT) (a blood clot in in one of the deep veins in the body, usually in one of the legs) and Pulmonary embolism (a blood clot in the blood vessel that carries blood from the heart to the lungs). Although serious, most blood clots can be completely avoided. The key is to be aware if you’re at risk and take some simple preventative steps.
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Meet Dr Shafeek


Anaemia Investigations
Cytopenia – Low White cell count or Platelets
Immune Thrombocytopenia
Obstetric Haematology
Thrombosis & Haemostasis – Deep Vein Thrombosis/ Pulmonary Embolism / Easy Bruising / Familial Thrombosis
Non-Hodgkin’s Lymphoma (High Grade & Low Grade)
Hodgkin’s Lymphoma
Acute Myeloid Leukaemia
Acute Lymphoblastic Leukaemia
Chronic Lymphocytic Leukaemia
Chronic Myeloid Leukaemia
Hyper Eosinophilic Syndrome
Systemic mastocytosis
Paroxysmal Nocturnal Haemoglobinuria
Myelodysplastic Syndrome
Myeloproliferative Disorders
(Primary Polycythaemia, Essential Thrombocythaemia & Myelofibrosis)
Other lymphoproliferative disorders (eg Waldenstrom’s macroglubulinaemia, hairy cell leukaemia)
Patients undergoing autologous stem cell transplantation (Shared Care with Queen Elizabeth Hospital Birmingham)
Patients undergoing allogeneic stem cell transplantation (Shared Care with Queen Elizabeth Hospital Birmingham)